LTA (lymphotoxin-A)
نویسندگان
چکیده
منابع مشابه
Lymphotoxin Alpha (LTA) Polymorphism Is Associated with Prognosis of Non-Hodgkin’s Lymphoma in a Chinese Population
BACKGROUND Non-Hodgkin's lymphoma (NHL) has been widely reported to be associated with autoimmune and pro-inflammatory response, and genetic polymorphisms of candidate genes involved in autoimmune and pro-inflammatory response may influence the survival and prognosis of NHL patients. To evaluate the role of such genetic variations in prognosis of NHL, we conducted this study in a Chinese popula...
متن کاملP2Y2 Receptor-mediated Lymphotoxin-α (LTA) Secretion Regulates Intercellular Cell Adhesion Molecule (ICAM)-1 Expression in Vascular Smooth Muscle Cells
Capsule Background: Lymphotoxin-alpha (LTA) is involved in the pathogenesis of atherosclerosis. Results: The P2Y2 nucleotide receptor (P2Y2R) recruits filamin A to activate Rho signaling upstream of LTA secretion leading to intercellular cell adhesion molecule-1 expression. Conclusion: P2Y2R regulates LTA gene activation and secretion in vascular smooth muscle cells. Significance: This suggests...
متن کاملDisciple‐lta: Analyst's Cognitive Assistant Disciple‐lta: Analyst's Cognitive Assistant
Disciple‐LTA is a personal cognitive assistant to an intelligence analyst that addresses several systemic problems associated with the current analytic process related to effective analytic assistance, capturing of analytic expertise, and tutoring new analysts. Disciple‐LTA can rapidly acquire and maintain analytic expertise which currently takes years to establish, is lost when analysts separa...
متن کاملMeta- and Pooled Analyses Tumor Necrosis Factor (TNF) and Lymphotoxin-a (LTA) Polymorphisms and Risk of Non-Hodgkin Lymphoma in the InterLymph Consortium
Christine F. Skibola*, Paige M. Bracci, Alexandra Nieters, Angela Brooks-Wilson, Silvia de Sanjosé, Ann Maree Hughes, James R. Cerhan, Danica R. Skibola, Mark Purdue, Eleanor Kane, Qing Lan, Lenka Foretova, Maryjean Schenk, John J. Spinelli, Susan L. Slager, Anneclaire J. De Roos, Martyn T. Smith, Eve Roman, Wendy Cozen, Paolo Boffetta, Anne Kricker, Tongzhang Zheng, Tracy Lightfoot, Pierluigi ...
متن کاملA Staphylococcus aureus ypfP mutant with strongly reduced lipoteichoic acid (LTA) content: LTA governs bacterial surface properties and autolysin activity
Many Gram-positive bacteria produce lipoteichoic acid (LTA) polymers whose physiological roles have remained a matter of debate because of the lack of LTA-deficient mutants. The ypfP gene responsible for biosynthesis of a glycolipid found in LTA was deleted in Staphylococcus aureus SA113, causing 87% reduction of the LTA content. Mass spectrometry and nuclear magnetic resonance spectroscopy rev...
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ژورنال
عنوان ژورنال: Atlas of Genetics and Cytogenetics in Oncology and Haematology
سال: 2011
ISSN: 1768-3262
DOI: 10.4267/2042/38178